Author(s) :

Jihyeong Kim, Shin Seo.

Volume/Issue :

Abstract :

Parabens and phthalates are increasingly under scrutiny for their adverse biological effects owing to their ever-widening application in the fields of cosmetics and personal care products. As endocrine disruptors, these chemicals mimic estrogen, bind to hormone receptors, and cause changes in relevant cellular pathways that may lead to cancer development. Parabens and phthalates are believed to stimulate breast cancer cell proliferation, interfere with apoptosis, and activate signaling pathways such as PI3K/AKT, according to in vitro experiments. Such chemicals can be detected in breast tissues and urine, and concentrations associated with increased risk of hormone receptor-positive breast cancer have been confirmed in both studies of environmental contaminants and human population exposures. Moreover, the consequences of exposure extend far beyond personal health impacts, impacting more subtly upon public health and environmental justice. Culturally toxic advertising strategies contribute to restricted access to safer alternatives, hurting women of color and low-incidence populations the most. With inadequate testing on chemical components not being mandated by US regulations, vulnerable communities remain unprotected. The review will consider mechanisms of action for parabens and phthalate toxins, their impact on breast cancer biology, and how those risks may interact with patterns of social inequality. If these issues are truly to be addressed, comprehensive regulation, consumer awareness, and health equity research are required. The reckless use of these chemicals brings the urgency of public health intervention and policy conciseness without further delay to prevent any preventable harm and create a safer environment for all population strata.