| 1 |
Author(s):
Isabella Chen.
Page No : 1-5
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Expansion of K-pop in Global Market
Abstract
K-pop has made outstanding achievements in the global market from multiple aspects. This study analyzes the global market strategies that have propelled K-pop groups to the international stage: these strategies have enabled K-pop groups to link cultural and national boundaries effectively. The success of incorporating multicultural elements retains the group's Korean identity while appealing to a broad, global audience. Digital and social media initiatives facilitate direct engagement with fans worldwide and build a loyal and expansive following. Unique brand narratives and identities further help these groups to stand out in a competitive global market. The insights gathered from this study offer valuable approaches for cultural products seeking global market success and cultural acceptance.
| 2 |
Author(s):
Anthony J Zhong and Guantong Li.
Page No : 6-10
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Anti-tumor Effects of Triptonide Derived from Chinese Herb Tripterygium Wilfordii Hook F
Abstract
Tripterygium wilfordii Hook F (TwHF), a traditional Chinese herb, has been used to treat autoimmune and inflammatory diseases for centuries. In the past decades, anti-tumor effects of two key ingredients of TwHF, triptolide and celastrol, have been reported in numerous research studies and review articles. However, the importance of triptonide (another important ingredient of TwHF) in cancer therapy has not been recognized until recent years. In the article, we review recent advances of triptonide as an antitumor agent with a focus on its biological activities, action mechanisms and clinical development.
| 3 |
Author(s):
Jiarong Liu .
Page No : 11-13
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Should the US Government Fund Human Embryonic Stem Cell Research?
Abstract
Human embryonic stem (ES) cells isolated from human embryos are pluripotent and they have the remarkable ability to differentiate into all different cell types in the human body, thus holding enormous potential for therapeutic applications. But the use of human ES cells has been a topic of ethical and legal debate as it involves the destruction of human embryos. In addition, Immune rejection is another major concern when using human ES cells or their derived other cells as therapies in transplantation. The breakthrough in stem cell research came when human induced pluripotent stem cells (iPSCs) were discovered in 2007. Human iPSCs, like ES cells, have the potential to differentiate into all cell types in the human body, but don’t involve any human embryos. In addition, it is generally believed that human iPS cells reprogrammed from a patient's own somatic cells would reduce the risk of immune rejection when they or their-derived cells are transplanted back to the same patient. Since the discovery of human iPS cells, a question remains whether the US Government continues to fund human ES cell research. In this article, I discuss this question from three perspectives, the cell originating sources and immunogenicity, clinical trial results and safety for disease treatments.
| 4 |
Author(s):
Peiyao Ning.
Page No : 14-18
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From Gamers to Spectators: Exploring the Interplay Between Online Esports Viewership and the China Anti-Addiction System in Gaming
Abstract
Video Gaming among minors can bring both enjoyment and concern. Gaming offers opportunities for entertainment, social interaction, and even skill development. However, excessive gaming among young people could lead to addiction resulting in issues like neglecting responsibilities, disrupted sleep patterns, and emotional disturbances. China has implemented the Anti-Addiction System to curb gaming addiction among minors which limits the amount of time minors can spend playing online games to promote healthier gaming habits and reduce the potential negative impacts of excessive gaming on their well-being. However, the effectiveness of China's anti-addiction system remains unknown. This study aims to examine the effectiveness of China’s Anti-Addiction System in preventing gaming addiction among Chinese youths by assessing their game time in relation to online esports spectatorship. Using an online questionnaire, this study aims to assess the potential relationship between the effects of China’s Anti-Addiction System and online esports spectatorship among Chinese youth between ages of 15 to 17 (n = 33). Data were collected on participants’ game time after restriction by China’s Anti-Addiction System and their time spent watching esports online. Additional Likert scale questions further assessed the potential relationship. The collected data was subject to linear regression analysis and statistical hypothesis tests. This study discovered that there lacks convincing evidence of a relationship between the game time influenced by the Anti-Addiction System and online esports spectatorship. Results from this study reveals that China’s Anti-Addiction System does not have a substantial influence on the online esports spectating behaviors of underage Chinese gamers. Continued research and observations in this area are necessary to develop more effective strategies for the prevention of gaming addiction among underaged gamers.
| 5 |
Author(s):
Yihao He and Yu Qiu.
Page No : 19-22
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HAAH Is a Potential Diagnostic Biomarker for Esophageal Carcinoma
Abstract
The human aspartyl-asparaginyl-β-hydroxylase (HAAH) is typically overexpressed in various types of cancer but remains undetectable or expressed at very low levels in most normal mature tissues. This suggests that HAAH could serve as a potential biomarker for cancer diagnosis. In this study, we examined 23 esophageal carcinoma tissues and 23 adjacent non-tumor tissues using semi-quantitative RT-PCR to detect HAAH mRNA expression. Our findings revealed that HAAH mRNA expression was detectable in all 23 esophageal cancer specimens (100%), while it was absent in 4 adjacent non-tumor tissue samples. Furthermore, HAAH was overexpressed in 17 esophageal carcinoma specimens (73.9%), compared to only 3 normal non-tumor tissue specimens (13%). These results strongly suggest that the HAAH gene is frequently overexpressed in esophageal carcinoma, providing support for its potential as a diagnostic marker for this condition.