Author(s) :

Gaeun Jang, Angelina Jiale Ding, Judy Song, Wendi Zhang, Jayden Junpyo Ku, Jiayu Wu, Joseph Mingde Liu.

Volume/Issue :

Abstract :

Benzalkonium chloride (BAC) is a widely used quaternary ammonium compound with broadspectrum antimicrobial properties; however, its effectiveness against veterinary oral bacteria remains underexplored. This study evaluated the antibacterial activity of BAC at concentrations of 0.1%, 0.5%, 1%, 3%, and 5% using disk diffusion assays on bacterial isolates obtained from a feline oral sample. A descriptive trend of increasing inhibition zone diameter was observed with increasing concentration, ranging from 12 mm at 0.1% to 29 mm at 5%. These findings suggest concentration-dependent antibacterial activity within the tested range. However, due to methodological limitations, including a lack of bacterial identification, the absence of statistical testing, and the use of a single biological sample, results should be interpreted cautiously. This study provides preliminary evidence supporting BAC’s potential as an oral antiseptic in veterinary contexts and highlights the need for further controlled investigations.