Author(s) :

Christina Feng.

Volume/Issue :

Abstract :

Neural probes greatly assist us in our journey of learning about the brain by revealing the functioning of neurons. Probes are implanted in different areas of the brain to record data or to stimulate those sites. This detection and intervention of neural activity allows probes to diagnose and treat diseases. Probe technologies have advanced over time and opened new avenues in neural engineering. However, the appearance of a foreign object in the brain elicits a negative reaction that harms the brain and its components. To minimize this reaction, scientists utilize a variety of methods and designs that have yet to be perfected. This review aims to highlight the influence of neural probe designs on the foreign body response. This includes looking at existing types of probes and exploring their potential. The effects of different flexibilities, materials and sizes of neural probes will be examined using studies and research made by scientists to decipher what methods minimize the negative response the most. This paper also aims to identify the gaps in our current knowledge of this subject.